Polyethylene Glycol (PEG) -400
Polyethylene Glycol - 400 is a low molecular weight grade of polyethylene glycol. It is a clear, colourless, viscous liquid. Due to its low toxicity, it is widely used in a variety of pharmaceutical formulations.
- Other Names
- Propylene Glycol, PEG - 400
- Chemical Formula
- C2nH4n+2On+1;n=8.3 to 9.2
- CAS No
- 25322-68-3
- Molar Mass
- 380 - 420 g/mol
| TEST | RESULT |
|---|---|
| Appearance | Clear Colourless Viscous Liquid |
| Molecular Weight | 380 - 420 |
| Specific Gravity At 25°C | 1.112 – 1.125 |
| Water | 1 % - max |
| Melting point | 4 - 10 °C |
| pH | 4 - 7 |
| Hydroxyl value | 264 – 300 |
Applications:
Polyethylene Glycol - 400 are widely used in variety of pharmaceutical formulations including parenteral, topical, oral and recta preparations.
It is used as a water miscible solvent for the contents of soft gelatin capsules. They may cause hardening of the capsule shell by preferential absorption of moisture from gelatin in shell.
Used as the vehicle for parenteral dosage forms.
It is used in skin creams and toothpastes as combined with glycerine.
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